Systematic profiling of single-, double- and triple-halogen substitution effects on the mononucleotide binding of N6-methyladenosine to human RNA m6A reader YTHDF1.

N6-methyladenosine (m6A) is the most plentiful internal modification event in eukaryotic RNAs and regulated dynamically by a variety of its cognate functional partners in a context-dependent manner, namely writers, erasers and readers. The YTHDF1 is…

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