Natural product research
Isolation of a novel bufadienolide, bufovende A, and seven known analogs from Venenum bufonis with inhibitory activity on hepatic stellate cell activation.
Huijing Lv, Chengjin Li, Qinggui Li, Qingqing Luo, Yunsong Chen, Anli Liu, Xinyi Du, Qian Cao, Pengwei Zhang, Lingjie Meng
Published: 202510.1080/14786419.2025.2567641
Abstract
As the principal bioactive constituents of Venenum Bufonis (VB), bufadienolides mediate the therapeutic efficacy of this traditional Chinese medicine in diverse clinical applications. In this study, a novel bufadienolide, designated as bufovende A (1…
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