Expert opinion on drug safety
Analysis of risk factors and development of a predictive model for significant serum creatinine elevation in patients administered SGLT2 inhibitor in a real-world clinical setting in China.
Hao Xie, Rui Dai, Yixun Shi, Xinyu Du, Zhiqing Xu, Xiaoli Du, Gang Chen, Bin Zhao
Published: 202510.1080/14740338.2025.2569123
Abstract
BACKGROUND: Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are widely used, but may lead to significant serum creatinine elevation ( > 30%), posing a risk of acute kidney injury. RESEARCH DESIGN AND METHODS: A retrospective analysis was conducted…
Preview only. Read the full abstract at the source