Pharmacogenomics
Association of CYP2C19 gene single nucleotide polymorphisms (rs12248560 and rs4244285) with response to thalidomide in transfusion dependent β-thalassemia patients- a 12-months follow-up study.
Inayat Ur Rahman, Muhammad Shahid, Muhammad Tariq Humayun Khan, Naseer Ahmed, Shafiq Ahmad, Amir Muhammad, Sher Afghan Khan, Abdus Saboor, Muhammad Tariq Masood Khan, Sami Siraj
Published: 202610.1080/14622416.2026.2622318
Abstract
AIM: This study aimed to evaluate the efficacy of thalidomide in transfusion-dependent β-thalassemia (TDT) patients and explore its association with CYP2C19 polymorphisms (rs12248560 and rs4244285). METHODS: Hemoglobin levels of 190 TDT patients were…
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