Pharmacogenomics
ATP-binding cassette transporter polymorphisms and the pharmacokinetics of oral esketamine.
Jerome Oude Nijhuis, Daniël Coerts, Jens van Dalfsen, Sanne Smith-Apeldoorn, Jolien Veraart, Robert Schoevers, Daan J Touw, Ron van Schaik
Published: 202610.1080/14622416.2026.2617376
Abstract
Oral esketamine is a promising new therapy for treatment-resistant depression. However, concerns exist about interindividual pharmacokinetic variability. Genetic polymorphisms regulating the expression of ATP-binding cassette (ABC) transporters might…
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