The Role of the RhoA Activating Protein Net1 in Cancer Initiation and Progression.

Rho GTPases are Ras-like proteins that contribute to many aspects of human cancer. However, unlike Ras, Rho proteins are not often mutagenically activated in cancers, but require activation by upstream proteins known as Rho GDP exchange factors (RhoG…

Preview only. Read the full abstract at the source