Molecular and cellular biology
Enhanced ELL Phase Separation Is Crucial for Efficient DNA Damage Repair to Restart Transcription and Cell Survival.
Sujay Pal, Prathama Talukdar, Arijit Ghosh, Sangheeta Bhattacharjee, Sumangal Roychowdhury, Pamela Pal, Anupam Gautam, Subham Basu, Sandip Paul, Krishnananda Chattopadhyay, Benu Brata Das, Debabrata Biswas
Published: 202510.1080/10985549.2025.2597497
Abstract
During genotoxic stress, mammalian cells adapt to resume transcription after repair of damaged DNA. However, mechanisms of these adaptations leading to optimal transcriptional restart are poorly known. In this study, we show critical role of EAF1-med…
Preview only. Read the full abstract at the source