Molecular and cellular biologyHumansTumor MicroenvironmentELAV-Like Protein 1Pancreatic NeoplasmsCarcinoma
The Role of Tumor-Intrinsic HuR in Modeling the Pancreatic Tumor Microenvironment: Molecular Mechanisms and Therapeutic Opportunities.
Katherine R Pelz, Kyle P Gribbin, Tess Sevetson, Jonathan R Brody
Published: 202510.1080/10985549.2025.2557414
Abstract
Pancreatic ductal adenocarcinoma (PDAC) remains largely refractory to therapy, due in part to the complex interplay between tumor cells and their microenvironment. Human antigen R (HuR/ELAVL1), a ubiquitously expressed RNA-binding protein, is emergin…
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