In vitro antifungal and antibiofilm evaluation of reduction-responsive ketoconazole-loaded nanoparticles based on cystamine-modified poly (isobutene-alt-maleic anhydride) polymer.

PURPOSE: In order to develop reduction-responsive nano-drug delivery system for encapsulating antifungal drugs. METHODS: Herein, with poly (isobutene-alt-maleic anhydride) as skeleton, we synthesized a polymer containing cross-linked disulfide bonds…

Preview only. Read the full abstract at the source