Therapeutic effect of topiramate on paroxysmal tonic spasms in a Chinese woman with neuromyelitis optica spectrum disease: A case report.

Context: Painful tonic spasms (PTS) are a common symptom in patients with neuromyelitis optica spectrum disease (NMOSD). Antiepileptic drugs (AEDs) such as carbamazepine serve as first-line therapeutic agents for PTS. However, hypersensitivity reacti…

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