Clinical and experimental hypertension (New York, N.Y. : 1993)AnimalsHSP90 Heat-Shock ProteinsProto-Oncogene Proteins c-aktPhosphorylationCell Proliferation
Interaction of circPcmtd1 with HSP90AB1 mediates phosphorylation of AKT to regulate pulmonary arterial hypertension induced by high pulmonary blood flow in rat.
Bingbing Ye, Danyan Su, Yuqin Huang, Dongli Liu, Yanyun Huang, Suyuan Qin, Cheng Chen, Yusheng Pang
Published: 202510.1080/10641963.2025.2583193
Abstract
This study was designed to elucidate the role of circPcmtd1 in regulating pulmonary artery smooth muscle cells (PASMCs) proliferation and migration, through the HSP90AB1/AKT signaling axis, in rats with high pulmonary blood flow-induced PAH. A rat mo…
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