Journal of drug targeting
Targeted colon cancer therapy using lapatinib-encapsulated chitosan nanoparticles conjugated with lactoferrin and melatonin with integrated in silico in vitro and in vivo evaluation.
Upasana, Sankha Bhattacharya, Vishal Beldar, Preeti Chidambar Sangave, Shashikant Bagade, Satyam Sharma, Rehan Khan
Published: 202510.1080/1061186X.2025.2578296
Abstract
Colorectal cancer is major cause of mortality, necessitating improved treatments. Lapatinib-loaded chitosan nanoparticles conjugated with lactoferrin and melatonin (LAP-CS-LF-MLT-NPs) developed using ionic gelation and carbodiimide coupling to improv…
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