Journal of drug targeting
Fisetin topical delivery via ascorbyl palmitate/hyaluronan-enhanced limosomes: a novel paradigm for preventing UVB-induced skin photoaging.
Asmaa H Elwan, Soha M El-Masry, Doaa A Habib, Marwa M Essawy, Mariam Zewail
Published: 202510.1080/1061186X.2025.2573053
Abstract
This study investigates the topical delivery of Fisetin (FIS) to counteract UVB-induced skin photoaging. Due to FIS's poor solubility and high lipophilicity, it was encapsulated in D-limonene-modified phospholipid carriers, limosomes (LIMOs), co-form…
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