Journal of biopharmaceutical statistics
The proportional treatment effect: A metric that empowers and connects.
Guoqiao Wang, Yijie Liao, Caiyan Li, Kun Jin, Yan Li, Gary Cutter
Published: 202510.1080/10543406.2025.2602479
Abstract
Clinical trials with continuous endpoints evaluate efficacy by comparing the difference in mean changes from baseline between groups. However, clinicians often interpret results in terms of a proportional reduction rather than an absolute difference.…
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