Leukemia & lymphoma
Treatment kinetics and local response during and after bridging radiotherapy prior to CAR-T cell therapy for lymphomas.
Daniella Klebaner, Natalie J Park, Mallika Marar, Matthew Frank, Susan M Hiniker, Richard T Hoppe, Joseph Schroers-Martin, Ranjana H Advani, Ash A Alizadeh, Sushma Bharadwaj, David Miklos, Saurabh Dahiya, Michael Sargent Binkley
Published: 202510.1080/10428194.2025.2602880
Abstract
Bridging radiotherapy (BR) prior to CAR-T for non-Hodgkin lymphoma (NHL) can achieve durable cytoreduction, but optimal dosing remains undefined. We evaluated correlates of local progression (LP) among 33 patients (25 large B-cell lymphoma [LBCL], 8…
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