Leukemia & lymphomaHumansMicroRNAsSirtuin 1FerroptosisLymphoma
MiR-22-3p regulates the SIRT1/P53 signaling pathway, thereby influencing ferroptosis in diffuse large B-cell lymphoma cells.
Xin Lu, Liyun Zhao, Suli Guo, Nafei Chen, Yehua Zhang, Ran Chen, Jiang Licai, Zongjiu Jiao
Published: 202610.1080/10428194.2025.2568186
Abstract
Diffuse large B-cell lymphoma (DLBCL) is an aggressive non-Hodgkin lymphoma with high mortality. Ferroptosis, an iron-dependent form of programmed cell death, has potential in cancer therapy. This study investigates the role of miR-22-3p in regulatin…
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