Computer methods in biomechanics and biomedical engineering
Unraveling the impact of alternative splicing network on cancer immune microenvironment and tumor development: unique insights from Drosophila homologous genes within human genome.
Xiao Zhu, Mengmeng Zhang, Qinglan Chen, Yangda Xiao, Guoqiang Xu, Lianzhou Chen
Published: 202510.1080/10255842.2025.2601835
Abstract
Alternative splicing (AS) generates diverse mRNA isoforms and plays a key role in cancer. Using Drosophila homologous genes, this study identified prognostic AS events across pan-cancer via Cox regression and constructed robust prognostic signatures…
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