Computer methods in biomechanics and biomedical engineering
A theoretical study of dielectrophoretic effects on septins during cytokinesis under tumor treating fields.
Liang Wang, Yueyue Xiao, Chunxiao Chen, Xue Fu, Rongfang Gong, Jun Shen, Ming Lu
Published: 202510.1080/10255842.2025.2578322
Abstract
This study investigates how Tumor Treating Fields (TTFields) disrupt tumor cell division by exerting dielectrophoretic (DEP) forces on septins, key proteins in cytokinesis. Computational models show that TTFields induce negative DEP forces, displacin…
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