International review of psychiatry (Abingdon, England)HumansKetamineAdolescentMajor Depressive DisorderAntidepressive Agents
Ketamine for major depression in adolescents: a systematic review and meta-analysis of efficacy and safety.
Iury P A Magalhães, Daniel N Lopes, Isabel Amato, Marcos V V Ribeiro, Rodrigo Luz, Acioly L T Lacerda, Elson Asevedo, Camila B Martins, Sheila C Caetano
Published: 202510.1080/09540261.2025.2581238
Abstract
Major depressive disorder (MDD) significantly impairs adolescents' development, with increasing rates of treatment resistance and suicide risk. Ketamine has emerged as a promising, rapid-acting antidepressant in adults, but its efficacy and safety in…
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