Novel compound heterozygous ITGA2B mutations in Glanzmann thrombasthenia associated with adolescent osteoporosis.

Glanzmann thrombasthenia (GT), caused by defects in integrin αIIbβ3, is characterized by impaired platelet aggregation. While αIIbβ3 dysfunction is well-documented in hematologic pathology, its association with bone metabolism remains controversial.…

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