Gynecological endocrinology : the official journal of the International Society of Gynecological EndocrinologyHumansFemaleHypoxia-Inducible Factor 1alpha SubunitVascular Endothelial Growth Factor A
Hypoxia-preconditioned hUCMSCs protect frozen-thawed human ovarian tissue by modulating the HIF-1α/VEGF pathway.
Muqing Gu, Xiangyan Ruan, Jiaojiao Cheng, Yanglu Li, Yanqiu Li, Juan Du, Fengyu Jin, Yinmei Dai, Alfred Otto Mueck
Published: 202510.1080/09513590.2025.2597612
Abstract
OBJECTIVE: To evaluate whether hypoxia-preconditioned human umbilical cord mesenchymal stem cells (hUCMSCs) can protect frozen-thawed human ovarian tissue via in vitro co-culture. METHODS: Frozen-thawed ovarian cortical pieces from 10 patients were r…
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