Development of icariin-loaded bone-targeting liposomes and its anti-osteoporosis effects and mechanism.

Osteoporosis increases fracture risk, necessitating safe therapies. Icariin has anti-osteoporosis effects but exhibits poor solubility, short circulation, and lack of bone targeting. We developed tetracycline (TC)/1,2-distearoyl-sn-glycero-3-phosphoe…

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