Folate-targeted long-circulating 5-fluorouracil liposomes: preparation, characterization, anti-tumor effect and pharmacokinetic profile in rats.

5-Fluorouracil (5-Fu) is a chemotherapy drug that can treat various cancers. However, its short plasma half-life and severe adverse reactions limit its wide application in clinical utility. To overcome these drawbacks, in this study, 5-Fu long-circul…

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