Growth factors (Chur, Switzerland)AnimalsDNA (Cytosine-5-)-Methyltransferase 1MiceReceptorNotch2
DNA methyltransferase 1-mediated methylation of midkine regulate myocardial ischemia-reperfusion injury via the Notch2/Hes1 axis.
Wei Liu, Yuqin Wang, Jiayuan Wu, Caihong He, Zhengwei Zhou
Published: 202510.1080/08977194.2025.2595011
Abstract
myocardial ischemia-reperfusion injury (MI/RI) threatens people's lives. Midkine (MDK) has a protective effect against MI/RI. DNA methyltransferase 1 (DNMT1) is closely associated with MI/RI. Mouse cardiomyocytes were isolated to establish a model of…
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