Blood pressureHumansPerindoprilHypertensionMiddle AgedProspective Studies
Differences in antihypertensive drug blood levels in patients with hypertension (DECISION): a prospective study comparing pharmacokinetics and pharmacodynamics of perindopril in younger and older patients.
Dimokrat Hassan, Laura E J Peeters, Wim J R Rietdijk, Bart van Domburg, Soma Bahmany, Sebastiaan D T Sassen, Dennis A Hesselink, Arend F L Schinkel, Olivier C Manintveld, Tjebbe W Galema, Jeroen B van der Net, Melvin Lafeber, Talip Tumkaya, Birgit C P Koch, Jorie Versmissen
Published: 202510.1080/08037051.2025.2580368
Abstract
AIM: To investigate age-related differences in the pharmacokinetics (PK) and pharmacodynamics (PD) of perindopril. METHODS: We compared the PK/PD of perindopril between younger (<50 years) and older (>70 years) participants in a prospective study. Th…
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