Journal of biomolecular structure & dynamics
Structure-based virtual screening and experimental validation of a MARK4 inhibitor for targeted cancer therapy.
Sarfraz Ahmed, Mohd Shakir, Haider Thaer Abdulhameed Almuqdadi, Bhaskar Sharma, Afzal Hussain, Phool Hasan, Mukesh C Joshi, Diwan S Rawat, Md Imtaiyaz Hassan, Jihoe Kim, Parvez Khan, Mohammad Abid
Published: 202610.1080/07391102.2026.2618019
Abstract
Microtubule affinity-regulating kinase 4 (MARK4) is a viable therapeutic target for neurodegenerative disorders and various solid cancers. To identify small molecule inhibitors targeting MARK4, a virtual high-throughput screening of a kinase-specific…
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