Journal of biomolecular structure & dynamics
Computational analysis and molecular dynamics insights into deleterious SNPs of the HFE gene.
Md Sajedul Islam, Tasnim Hosen Tanha, Nazia Zarin, Shaila Haque, Muhammad J A Shiddiky, Alfred K Lam, Vinod Gopalan
Published: 202510.1080/07391102.2025.2593504
Abstract
Mutations in the HFE gene, especially non-synonymous single-nucleotide polymorphisms (nsSNPs), are strongly associated with hemochromatosis, an autosomal recessive disorder characterized by intracellular iron overload, a key feature of tumor developm…
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