Journal of biomolecular structure & dynamics
An integrative computational study of marine natural products as selective inhibitors of HPV16 and HPV18 E6/E7 oncoproteins: structural and energetic insights from PCA-based free energy landscape analysis.
Appala Krishna Chaitanya Gundu, Govindaraju Kasivelu, Santhiya Panchalingam, Sri Venu Madhav Tippabhotla
Published: 202510.1080/07391102.2025.2578228
Abstract
Human papillomavirus (HPV) is a well-established causative agent in cervical as well as in a few other anogenital and oropharyngeal cancers. Of the many genotypes, HPV16 and HPV18 are the most oncogenic, individually responsible for more than half of…
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