An in-silico analysis of the interaction between selected honey bee venom peptides and the murine MHC-hMOG37-46 complex for investigating potential therapeutic approaches in multiple sclerosis.

The cellular immune responses associated with multiple sclerosis are triggered when T-lymphocyte receptors interact with the MOG epitope-MHC complex. By inhibiting the formation of this harmful trimeric complex (MHC-epitope-TCR), it is possible to al…

Preview only. Read the full abstract at the source