The Journal of asthma : official journal of the Association for the Care of Asthma
Ex vivo air-liquid interface respiratory mucosa platform to study type 2-driven asthma.
Giorgia Intili, Alberto Fucarino, Stefano Burgio, Maria Denise Amico, Domenico Michele Modica, Salvatore Poma, Olga Maria Manna, Alida Benfante, Alessandra Tomasello, Nicola Scichilone, Fabio Bucchieri, Alessandro Pitruzzella
Published: 202610.1080/02770903.2025.2608988
Abstract
OBJECTIVE: Asthma is a heterogeneous disorder in which a subset of patients exhibits a type 2 (Th2- or T2-high) endotype driven by eosinophilic, IL-4/IL-13-mediated inflammation. Traditional animal and 2D cell-based models incompletely reproduce huma…
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