Melatonin regulates the MST1/Nrf2 pathway to alleviate oxidative stress injury after hypoxic-ischemic brain damage in neonatal rats.

OBJECTIVE: Oxidative stress is a key factor in neonatal hypoxic-ischemic encephalopathy (HIE). Despite the widespread attention on melatonin (Mel) as a potential therapeutic agent, its antioxidative mechanisms in HIE remain incompletely understood. T…

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