Acta cardiologica
Role SGLT2 inhibitor therapy in patients with transthyretin cardiac amyloidosis: a GRADE assessed systematic review and meta-analysis.
Ahmed Ali Khan, Muhammad Shaheer Bin Faheem, Fatima Wahid, Kalsoom Zulfiqar, Hajra Habib, Maheen Nawaz, Araiz Afridi, Salman Tariq, Muhammad Humayoon
Published: 202510.1080/00015385.2025.2594908
Abstract
BACKGROUND: Transthyretin amyloid cardiomyopathy (ATTR-CM) patients continue to experience worsening heart failure despite therapy with disease modifying therapies (tafamidis, patisiran, etc.). Given the proven benefits of SGLT2 inhibitors in heart f…
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