Reproduction, fertility, and development
Investigation of endocannabinoid 2-AG and its hydrolases for regulation on sperm motility and acrosome reaction in Kunming mice.
Xin Zhang, Wenjing Wu, Yahui Li, Minghua Yang
Published: 202610.1071/RD25040
Abstract
Context 2-AG (2-arachidonoyl glycerol), a key endocannabinoid, regulates sperm hyperactivation in humans via ABHD2 (alpha/beta hydrolase domain-containing protein 2)-mediated CatSper calcium channel activation. However, ABHD2's role in mice is unclea…
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