The Journal of chemical physicsAlgorithmsMolecular Dynamics SimulationProtein ConformationCalciumAmino Acid Sequence
Repetitive proteins that undergo large conformational changes evade structural prediction algorithms.
Marina P Chang, Tianyi Jin, Alana P Gudinas, Daniel Fernandez, Alfredo Alexander-Katz, Tsutomu Matsui, Danielle J Mai
Published: 202510.1063/5.0304777
Abstract
Protein structure prediction algorithms, such as AlphaFold, have accelerated protein design and advanced the understanding of the relationship between amino acid sequence and protein structure. However, these algorithms are limited in their ability t…
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