The Journal of chemical physicsAdenosine TriphosphateAdenosine TriphosphatasesMolecular Dynamics SimulationDNA-Binding ProteinsMultiprotein Complexes
Contact networks encode the ATP-induced dynamic structural asymmetry of condensin head domains.
Chengzhen Xu, Xiakun Chu
Published: 202510.1063/5.0295393
Abstract
Condensin, a structural maintenance of chromosomes (SMC) complex, plays a central role in genome organization by driving DNA loop extrusion through ATP hydrolysis. Experimental studies have revealed an asymmetric ATP-binding order at the Smc4- and Sm…
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