Gastroenterology
Mutational Landscape of Colorectal Tumors From Individuals With Unexplained Adenomatous or Serrated Colorectal Polyposis.
Anna K Sommer, Iris B A W Te Paske, Erik A M Jansen, Axel Gschwind, German Demidov, Verena Steinke-Lange, Isabel Spier, Wouter Steyaert, Burcu Yaldiz, Marloes Steehouwer, Oliver Hommerding, Dimo Dietrich, Sophia Peters, José Garcia-Pelaez, Andreas Laner
Published: 202610.1053/j.gastro.2025.10.011
Abstract
BACKGROUND & AIMS: Individuals with colorectal polyposis are suspected to be genetically predisposed to tumor development. However, in around half of adenomatous and the vast majority of serrated polyposis patients, no explanatory pathogenic germline…
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