Gastroenterology
Clusterin Drives Fiber Endocytosis by Mesothelial Cells to Resolve Liver Fibrosis.
Minjun Wang, Fei Chen, Junling Gao, Qinggui Liu, Zhixuan Li, Qingjie Kong, Yanfang Liu, Yan Pang, Zijun Wang, Ye Zhou, Liyuan Zhang, Kaiwei Jia, Shan Lu, Shanrong Liu, Jihang Yuan
Published: 202510.1053/j.gastro.2025.08.022
Abstract
BACKGROUND & AIMS: Liver fibrosis, a common outcome of chronic liver diseases, is generally considered irreversible. Upregulation of clusterin (CLU), a secreted glycoprotein, occurs in several degenerative diseases and is suggested to have protective…
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