Gastroenterology
Changes in Liver Disease Etiology Support a Lower Alpha-Fetoprotein Threshold for Hepatocellular Carcinoma Screening.
Nicole J Kim, Muyi Li, Philip Vutien, Bret Mecham, Joleen Borgerding, Kayta Swarts, Pranusha Atuluru, Martha C Michel, Abbey Barnard Giustini, Catherine Mezzacappa, Kristin Berry, Trang VoPham, Tracey L Marsh, Ziding Feng, Kay M Johnson
Published: 202510.1053/j.gastro.2025.08.021
Abstract
BACKGROUND & AIMS: Serum alpha-fetoprotein (AFP) is a key component of hepatocellular carcinoma (HCC) screening, but its test characteristics are uncertain as alcohol-associated liver disease (ALD) and metabolic dysfunction-associated steatotic liver…
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