The Biochemical journalPlasmodium falciparumSingle-Domain AntibodiesProtozoan ProteinsCrystallographyX-Ray
Crystal structure and nanobodies against domain 3 of the malaria parasite fusogen Plasmodium falciparum HAP2.
Frankie M T Lyons, Jill Chmielewski, Li-Jin Chan, Mikha Gabriela, Rainbow W B Chan, Amy Adair, Joshua Tong, Phillip Pymm, Kathleen Zeglinski, Quentin Gouil, Wai-Hong Tham, Melanie H Dietrich
Published: 202610.1042/BCJ20250297
Abstract
Malaria parasites are transmitted to humans through a bite from an infected female Anopheles mosquito. Within the mosquito midgut, malaria parasite gametes are activated and undergo fertilisation. If parasite fertilisation is perturbed, this stops th…
Preview only. Read the full abstract at the source