Organic & biomolecular chemistryHumansOligosaccharidesSerologic TestsEpitopesLeishmaniasis
Enabling the serodiagnosis of American tegumentary leishmaniasis using synthetic aminopentyl-galactofuranoside-containing oligosaccharide epitopes.
Carolina S Touloumdjian, Emelie E Reuber, Fabienne Weber, Renato E Uncos, Eleonora Elhalem, Ana Bellomo, María J Comin, Jorge D Marco, Peter H Seeberger, Lucía Gandolfi Donadío
Published: 202610.1039/d5ob01900a
Abstract
The diagnosis of American tegumentary leishmaniasis (ATL), caused primarily by Leishmania braziliensis in Latin America, remains difficult due to the lack of specific serological tools. Here, we report the chemical synthesis and immunological evaluat…
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