Organic & biomolecular chemistry
Rhodium-catalyzed Z-alkenylation of gem-difluoropropenes: access to fluorinated (1Z,4Z)-dienes.
Jiang-Min Yan, Kai-Xian Ma, Rui-Hong Chen, Xue-Mei Huang, Zi-Xin Ye, Qing-Hua Li, Tang-Lin Liu
Published: 202610.1039/d5ob01824b
Abstract
An effective method for constructing thermodynamically unstable 1Z,4Z-dienes via Rh-catalysed cross-coupling of allylic gem-difluorides with tertiary Z-allylic alcohols has been developed. The fluoride elimination of the gem-difluoride propenes and β…
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