Organic & biomolecular chemistry
C(3)-H alkenylation of quinoxalin-2(1H)-ones with Hantzsch esters and in silico studies.
Saurabh Kumar, Amit Kumar Pathak, Uma Devi Newar, Abhimanyu Nayak, Monjuri Bora, Hrishikesh Sarmah, Subrata Ghosh, Ram Awatar Maurya
Published: 202610.1039/d5ob01795e
Abstract
A novel and efficient method for the C(3)-H alkenylation of quinoxalin-2(1H)-ones has been developed using trifluoroacetic acid (TFA) as a Brønsted acid catalyst and Hantzsch esters (HEs) as the alkenylating agent. This metal-free protocol provides d…
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