Organic & biomolecular chemistry
Photoredox/NHC-catalyzed remote alkylation of γ-functionalized enals with N-substituted pyridinium salts.
Yuan-Yuan Xu, Chang-Chun Liu, Zhi-Hao Shen, Ben-Cai Dai, Jun-An Ma, Yang Zhou
Published: 202610.1039/d5ob01714a
Abstract
We report a dual photoredox/NHC-catalyzed method for the regioselective remote alkylation of γ-functionalized enals. Using abundant Katritzky pyridinium salts as alkyl radical precursors and γ-functionalized enals to form trienolate intermediates, th…
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