Cascade synthesis of 2,3-disubstituted quinazolinones from methyl anthranilates, isocyanides and arylboronic acids via NHC-palladium-catalyzed oxidative coupling reactions.

A palladium-catalyzed oxidative coupling reaction constitutes an attractive approach for synthesis of 2,3-disubstituted quinazolinones. However, poor functional group tolerance, low selectivity, and side reactions have hindered their practical applic…

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