Regioselective copper-catalyzed dearomative alkynylation of N-alkyl nicotinate and isoquinoline salts.

This report describes a copper-catalyzed, dearomative alkynylation of N-alkyl pyridinium and isoquinolinium salts with readily available terminal alkynes. The reaction proceeds under mild conditions to afford a range of six-membered N-heterocyclic sc…

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