Diastereoselective construction of azabicyclo[3.1.0]hexan-2-ones via a base-mediated cascade annulation of β-oxo-acrylamides with vinylsulfonium salts.

Herein, a DBU-mediated cascade annulation of β-oxo-acrylamides with vinylsulfonium salts has been achieved under mild reaction conditions. This methodology not only provides a direct route for the synthesis of highly functionalized azabicyclo[3.1.0]h…

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