Silver-catalyzed synthesis of polyfunctionalized 1,7- and 2,7-benzonaphthyridine scaffolds and access to perlolidine derivatives.

A regio- and chemoselective silver-catalyzed one-pot synthesis of benzo[b][1,7]- and benzo[c][2,7]-naphthyridines has been developed via a sequential Michael addition and silver-mediated cyclization strategy. The protocol exhibits excellent selectivi…

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