Organic & biomolecular chemistry
Enantioselective palladium-catalyzed carbonylation toward N-N axially chiral amides.
Ke-Jiao Li, Ying-Ying Geng, Fu-Jian Zhang, Xin-Yue Li, Jing-Wen Liu, Cheng-Gui Wu, Cheng-Tao Feng, Fan Teng
Published: 202510.1039/d5ob01298h
Abstract
N-N axially chiral amides are widely present in various bioactive molecules, yet their catalytic asymmetric synthesis remains a major and persistent challenge. In this work, we report a novel palladium-catalyzed enantioselective carbonylation reactio…
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