Organic & biomolecular chemistry
Synthesis of fused indolin-3-one derivatives via (3 + 2)-cycloaddition of in situ generated 3H-indol-3-one with nitrilimines, nitrile oxides and azomethine ylides.
Nikolai A Arutiunov, Anna M Zatsepilina, Kirill V Tolstov, Daria A Shtal, Daria S Momotova, Dmitrii A Aksenov, Nicolai A Aksenov, Alexander V Aksenov
Published: 202510.1039/d5ob01186h
Abstract
A regioselective (3 + 2)-cycloaddition between in situ generated 3H-indol-3-one and three types of 1,3-dipoles leading to three classes of condensed indole derivatives was developed. Two pathways of cycloaddition depending on the structure of the ini…
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