Nanoscale
Enhancing tumor ROS generation via nanozyme-amplified photodynamic therapy with oxygen-supplying bacterial OMVs.
Haibing Dai, Yongqi Wang, Xiang Chen, Jiale Zhu, Han Wang, Daizong Cui, Huibin Wu, Guan Huang, Ran Luo, Jianbo Yu, Weiqun Li, Min Zhao, Lin Mei
Published: 202610.1039/d5nr04621a
Abstract
In this study, OMV@Hb-Ce6-Mn was constructed by co-loading hemoglobin (Hb) and chlorin e6 (Ce6) onto OMVs, followed by modification with manganese dioxide (MnO2) nanoparticles. OMV@Hb-Ce6-Mn significantly suppressed tumor growth and elicited potent s…
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